Recombinant Human REXO1, His-tagged

• Cat.No.: REXO1-5048H
• Product Overview: Recombinant human REXO1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: REXO1 belongs to the REXO1/REXO3 family and contains 1 exonuclease domain. This protein seems to have no detectable effect on transcription elongation in vitro.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 22.3 kDa (198aa) confirmed by MALDI-TOF
• AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSIYAL DCEMSYTTYG LELTRVTVVD TDVHVVYDTF VKPDNEIVDY NTRFSGVTEA DLADTSVTLR DVQAVLLSMF SADTILIGHS LESDLLALKV IHSTVVDTSV LFPHRLGLPY KRSLRNLMAD YLRQIIQDNV DGHSSSEDAG ACMHLVIWKV REDAKTKR
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: REXO1
• Synonyms: REXO1; REX1, RNA exonuclease 1 homolog (S. cerevisiae); TCEB3BP1, transcription elongation factor B polypeptide 3 binding protein 1; RNA exonuclease 1 homolog; EloA BP1; elongin A binding protein 1; KIAA1138; elongin A-binding protein 1; elongin-A-binding protein 1; transcription elongation factor B polypeptide 3 binding protein 1; transcription elongation factor B polypeptide 3-binding protein 1; REX1; ELOABP1; EloA-BP1; TCEB3BP1
• Gene ID: 57455
• mRNA Refseq: NM_020695
• Protein Refseq: NP_065746
• MIM: 609614
• UniProt ID: Q8N1G1
• Chromosome Location: 19p13.3
• Pathway: Ribosome biogenesis in eukaryotes, organism-specific biosystem; Ribosome biogenesis in eukaryotes, conserved biosystem
• Function: exonuclease activity; hydrolase activity; nucleic acid binding