Recombinant Human RFX5 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | RFX5-332H |
Product Overview : | RFX5 MS Standard C13 and N15-labeled recombinant protein (NP_001020774) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
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Description : | A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008] |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 65.1 kDa |
AA Sequence : | MAEDEPDAKSPKTGGRAPPGGAEAG EPTTLLQRLRGTISKAVQNKVEGIL QDVQKFSDNDKLYLYLQLPSGPTTG DKSSEPSTLSNEEYMYAYRWIRNHL EEHTDTCLPKQSVYDAYRKYCESLA CCRPLSTANFGKIIREIFPDIKARR LGGRGQSKYCYSGIRRKTLVSMPPL PGLDLKGSESPEMGPEVTPAPRDEL VEAACALTCDWAERILKRSFSSIVE VARFLLQQHLISARSAHAHVLKAMG LAEEDEHAPRERSSKPKNGLENPEG GAHKKPERLAQPPKDLEARTGAGPL ARGERKKSVVESSAPGANNLQVNAL VARLPLLLPRAPRSLIPPIPVSPPI LAPRLSSGALKVATLPLSSRAGAPP AAVPIINMILPTVPALPGPGPGPGR APPGGLTQPRGTENREVGIGGDQGP HDKGVKRTAEVPVSEASGQAPPAKA AKQDIEDTASDAKRKRGRPRKKSGG SGERNSTPLKSAAAMESAQSSRLPW ETWGSGGEGNSAGGAERPGPMGEAE KGAVLAQGQGDGTVSKGGRGPGSQH TKEAEDKIPLVPSKVSVIKGSRSQK EAFPLAKGEVDTAPQGNKDLKEHVL QSSLSQEHKDPKATPPTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | RFX5 regulatory factor X, 5 (influences HLA class II expression) [ Homo sapiens (human) ] |
Official Symbol : | RFX5 |
Synonyms : | RFX5; regulatory factor X, 5 (influences HLA class II expression); DNA-binding protein RFX5; regulatory factor X 5; |
Gene ID : | 5993 |
mRNA Refseq : | NM_001025603 |
Protein Refseq : | NP_001020774 |
MIM : | 601863 |
UniProt ID : | P48382 |
Products Types
◆ Recombinant Protein | ||
Rfx5-001M | Recombinant Mouse Rfx5 protein, Myc/DDK-tagged | +Inquiry |
RFX5-002H | Recombinant Human RFX5 protein, Myc/DDK-tagged | +Inquiry |
Rfx5-5482M | Recombinant Mouse Rfx5 Protein, Myc/DDK-tagged | +Inquiry |
RFX5-3680R | Recombinant Rhesus Macaque RFX5 Protein, His (Fc)-Avi-tagged | +Inquiry |
RFX5-001H | Recombinant Human RFX5 protein, His-tagged | +Inquiry |
◆ Lysates | ||
RFX5-2396HCL | Recombinant Human RFX5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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