Recombinant Human RIOK2 Protein (G2-E552), His/GST tagged

• Cat.No.: RIOK2-1123H
• Product Overview: Recombinant Human 8His-GST-TEV-GG-RIOK2(G2-E552 end) Protein was expressed in Insect cell.

Specification

• Description: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function.
• Source: Insect cell
• Species: Human
• Tag: His/GST
• Form: Liquid
• Protein Length: G2-E552
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: RIOK2 RIO kinase 2 (yeast) [ Homo sapiens (human) ]
• Official Symbol: RIOK2
• Synonyms: RIOK2; RIO kinase 2 (yeast); serine/threonine-protein kinase RIO2; FLJ11159; RIO2
• Gene ID: 55781
• mRNA Refseq: NM_001159749
• Protein Refseq: NP_001153221
• UniProt ID: Q9BVS4