| Description : |
This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
65.7 kDa |
| AA Sequence : |
MLVGSQSFSPGGPNGIIRSQSFAGF SGLQERRSRCNSFIENSSALKKPQA KLKKMHNLGHKNNNPPKEPQPKRVE EVYRALKNGLDEYLEVHQTELDKLT AQLKDMKRNSRLGVLYDLDKQIKTI ERYMRRLEFHISKVDELYEAYCIQR RLQDGASKMKQAFATSPASKAARES LTEINRSFKEYTENMCTIEVELENL LGEFSIKMKGLAGFARLCPGDQYEI FMKYGRQRWKLKGKIEVNGKQSWDG EETVFLPLIVGFISIKVTELKGLAT HILVGSVTCETKELFAARPQVVAVD INDLGTIKLNLEITWYPFDVEDMTA SSGAGNKAAALQRRMSMYSQGTPET PTFKDHSFFSNLPDDIFENGKAAEE KMPLSLSFSDLPNGDCALTSHSTGS PSNSTNPEITITPAEFNLSSLASQN EGMDDTSSASSRNSLGEGQEPKSHL KEEDPEEPRKPASAPSEACRRQSSG AGAEHLFLENDVAEALLQESEEASE LKPVELDTSEGNITKQLVKRLTSAE VPMATDRLLSEGSVGGESEGCRSFL DGSLEDAFNGLLLALEPHKEQYKEF QDLNQEVMNLDDILKKTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
