Recombinant Human RLN1 Protein, His-tagged

• Cat.No.: RLN1-219H
• Product Overview: Recombinant Human RLN1 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin.
• Source: E. coli
• Tag: His
• Form: 50mM Tris, 8M Urea, pH8.0.
• Molecular Mass: 21 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RLN1 relaxin 1 [ Homo sapiens ]
• Official Symbol: RLN1
• Synonyms: RLN1; relaxin 1; relaxin 1 (H1); prorelaxin H1; H1; relaxin H1; preprorelaxin H1; RLXH1; bA12D24.3.1; bA12D24.3.2
• Gene ID: 6013
• mRNA Refseq: NM_006911
• Protein Refseq: NP_008842
• MIM: 179730
• UniProt ID: P04808