Recombinant Human RNASEH2A Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | RNASEH2A-4598H |
Product Overview : | RNASEH2A MS Standard C13 and N15-labeled recombinant protein (NP_006388) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 33.4 kDa |
AA Sequence : | MDLSELERDNTGRCRLSSPVPAVCR KEPCVLGVDEAGRGPVLGPMVYAIC YCPLPRLADLEALKVADSKTLLESE RERLFAKMEDTDFVGWALDVLSPNL ISTSMLGRVKYNLNSLSHDTATGLI QYALDQGVNVTQVFVDTVGMPETYQ ARLQQSFPGIEVTVKAKADALYPVV SAASICAKVARDQAVKKWQFVEKLQ DLDTDYGSGYPNDPKTKAWLKEHVE PVFGFPQFVRFSWRTAQTILEKEAE DVIWEDSASENQEGLRKITSYFLNE GSQARPRSSHRYFLERGLESATSLT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | RNASEH2A ribonuclease H2 subunit A [ Homo sapiens (human) ] |
Official Symbol : | RNASEH2A |
Synonyms : | RNASEH2A; ribonuclease H2, subunit A; Aicardi Goutieres syndrome 4, ribonuclease H2, large subunit; ribonuclease H2 subunit A; AGS4; RNASEHI; RNHIA; RNHL; RNase H(35); RNase H2 subunit A; RNase HI large subunit; ribonuclease HI subunit A; ribonuclease HI large subunit; ribonuclease H2, large subunit; ribonuclease HI, large subunit; aicardi-Goutieres syndrome 4 protein; JUNB; |
Gene ID : | 10535 |
mRNA Refseq : | NM_006397 |
Protein Refseq : | NP_006388 |
MIM : | 606034 |
UniProt ID : | O75792 |
Products Types
◆ Recombinant Protein | ||
Rnaseh2a-5537M | Recombinant Mouse Rnaseh2a Protein, Myc/DDK-tagged | +Inquiry |
RNASEH2A-7633M | Recombinant Mouse RNASEH2A Protein, His (Fc)-Avi-tagged | +Inquiry |
RNASEH2A-1257H | Recombinant Human RNASEH2A Protein, MYC/DDK-tagged | +Inquiry |
RNASEH2A-4723R | Recombinant Rat RNASEH2A Protein, His (Fc)-Avi-tagged | +Inquiry |
RNASEH2A-7627H | Recombinant Human RNASEH2A, His-tagged | +Inquiry |
◆ Lysates | ||
RNASEH2A-1515HCL | Recombinant Human RNASEH2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket