Recombinant Human RNF213 Protein, MYC/DDK-tagged

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Recombinant Human RNF213 Protein, MYC/DDK-tagged

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Cat.No. : RNF213-675H
Product Overview : Recombinant Human RNF213 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 118.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : RNF213 ring finger protein 213 [ Homo sapiens ]
Official Symbol : RNF213
Synonyms : RNF213; ring finger protein 213; C17orf27, chromosome 17 open reading frame 27 , KIAA1618 , moyamoya disease 2 , Moyamoya disease 2 , MYMY2; RING finger protein 213; KIAA1554; NET57; mysterin; ALK lymphoma oligomerization partner on chromosome 17; ALO17; MYMY2; MYSTR; C17orf27; KIAA1618; MGC9929; FLJ13051; MGC46622; DKFZp762N1115;
Gene ID : 57674
mRNA Refseq : NM_020954
Protein Refseq : NP_066005
MIM : 613768
UniProt ID : Q63HN8
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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