Active Recombinant Human RNF34 Protein, GST-tagged
Cat.No. : | RNF34-638H |
Product Overview : | Recombinant Human RNF34 fused with GST tag at N-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase RNF34, also named CARP1 (Caspases-8/10 Associated RING protein 1), acts as RING‑domain E3 ligases, ubiquitinates apical caspases and targets them for proteasome-mediated degradation. CARP gene silencing inhibits tumor cell survival and increases cancer cell sensitivity to the death ligand or chemotherapy-induced apoptosis. CARP proteins target the tumor suppressor p53 for degradation. RNF34 is also a negative regulator of the NOD1 pathway through direct interaction and ubiquitination of NOD1. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol |
Bio-activity : | 21 nmol/min/mg |
Molecular Mass : | 68 kDa |
Purity : | >80% |
Applications : | Ubiquitin Enzyme Assay, Western Blot |
Stability : | 1 year at - 70 centigrade from the date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ml |
Gene Name : | RNF34 ring finger protein 34, E3 ubiquitin protein ligase [ Homo sapiens ] |
Official Symbol : | RNF34 |
Synonyms : | RNF34; ring finger protein 34, E3 ubiquitin protein ligase; ring finger protein 34; E3 ubiquitin-protein ligase RNF34; FLJ21786; RIF; RIFF; caspase regulator CARP1; RING finger protein RIFF; FYVE-RING finger protein MOMO; caspases-8 and -10-associated RING finger protein 1; human RING finger homologous to inhibitor of apoptosis protein; RFI; hRFI; CARP1; CARP-1; |
Gene ID : | 80196 |
mRNA Refseq : | NM_025126 |
Protein Refseq : | NP_079402 |
MIM : | 608299 |
UniProt ID : | Q969K3 |
Products Types
◆ Recombinant Protein | ||
RNF34-3759R | Recombinant Rhesus Macaque RNF34 Protein, His (Fc)-Avi-tagged | +Inquiry |
RNF34-7684M | Recombinant Mouse RNF34 Protein, His (Fc)-Avi-tagged | +Inquiry |
RNF34-682H | Recombinant Human RNF34 Protein, MYC/DDK-tagged | +Inquiry |
RNF34-4740R | Recombinant Rat RNF34 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rnf34-5557M | Recombinant Mouse Rnf34 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
RNF34-2279HCL | Recombinant Human RNF34 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket