Recombinant Human RRBP1 Protein, MYC/DDK-tagged

Species :	Human
Source :	HEK293
Tag :	DDK&Myc
Description :	This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass :	108.5 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name	RRBP1 ribosome binding protein 1 homolog 180kDa (dog) [ Homo sapiens ]
Official Symbol	RRBP1
Synonyms	ES/130; ES130; hES; RRp
Gene ID	6238
mRNA Refseq	NM_001042576
Protein Refseq	NP_001036041
MIM	601418
UniProt ID	Q9P2E9