Recombinant Human RUVBL2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RUVBL2-3308H
• Product Overview: RUVBL2 MS Standard C13 and N15-labeled recombinant protein (NP_006657) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.2 kDa
• AA Sequence: MATVTATTKVPEIRDVTRIERIGAH SHIRGLGLDDALEPRQASQGMVGQL AARRAAGVVLEMIREGKIAGRAVLI AGQPGTGKTAIAMGMAQALGPDTPF TAIAGSEIFSLEMSKTEALTQAFRR SIGVRIKEETEIIEGEVVEIQIDRP ATGTGSKVGKLTLKTTEMETIYDLG TKMIESLTKDKVQAGDVITIDKATG KISKLGRSFTRARDYDAMGSQTKFV QCPDGELQKRKEVVHTVSLHEIDVI NSRTQGFLALFSGDTGEIKSEVREQ INAKVAEWREEGKAEIIPGVLFIDE VHMLDIESFSFLNRALESDMAPVLI MATNRGITRIRGTSYQSPHGIPIDL LDRLLIVSTTPYSEKDTKQILRIRC EEEDVEMSEDAYTVLTRIGLETSLR YAIQLITAASLVCRKRKGTEVQVDD IKRVYSLFLDESRSTQYMKEYQDAF LFNELKGETMDTSTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RUVBL2 RuvB like AAA ATPase 2 [ Homo sapiens (human) ]
• Official Symbol: RUVBL2
• Synonyms: RUVBL2; RuvB-like 2 (E. coli); RuvB (E coli homolog) like 2; ruvB-like 2; ECP51; INO80 complex subunit J; INO80J; reptin; Reptin52; Rvb2; RVB2; TIH2; TIP48; TIP49b; ECP-51; reptin 52; TAP54-beta; reptin52 protein; repressing pontin 52; RuvB (E coli homolog)-like 2; 48 kDa TBP-interacting protein; TBP-interacting protein, 48-KD; TIP60-associated protein 54-beta; 51 kDa erythrocyte cytosolic protein; erythrocyte cytosolic protein, 51-KD; 48 kDa TATA box-binding protein-interacting protein; CGI-46; REPTIN; TIP49B
• Gene ID: 10856
• mRNA Refseq: NM_006666
• Protein Refseq: NP_006657
• MIM: 604788
• UniProt ID: Q9Y230