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Recombinant Human S100A2, His-tagged

Cat.No. : S100A2-3725H
Product Overview : Total 108 AA. MW: 12.36 kDa (calculated). N-Terminal His-tag, 10 extra AA (highlighted).
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Cat. No. : S100A2-3725H
Description : Protein S100-A2 is a protein that in humans is encoded by the S100A2 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
Source : E. coli
Species : Human
Form : Filtered (0,4 μm) and lyophilized in 0.5 mg/mL in 20mM TRIS, 50mM NaCl, pH 7.5.
Purity : 95%, as determined by densitometric image analysis.
Reconstitution : Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Applications : Western blotting
Quality Control Test : BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein
Sequences of amino acids : MKHHHHHHAS MMCSSLEQAL AVLVTTFHKY SCQEGDKFKL SKGEMKELLH KELPSFVGEK VDEEGLKKLM GSLDENSDQQ VDFQEYAVFL ALITVMCNDF FQGCPDRP
Storage : Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
Pathways : Direct p53 effectors
Gene Name : S100A2 S100 calcium binding protein A2 [ Homo sapiens ]
Official Symbol : S100A2
Synonyms : S100A2; S100 calcium binding protein A2; CAN19; S100L; MGC111539; protein S100-A2; OTTHUMP00000032967; S100 calcium-binding protein A2; Protein S100-A2; Protein S-100L
Gene ID : 6273
mRNA Refseq : NM_005978
Protein Refseq : NP_005969
MIM : 176993
UniProt ID : P29034
Chromosome Location : 1q21
Function : calcium ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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