Recombinant Human SAR1B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SAR1B-2136H
• Product Overview: SAR1B MS Standard C13 and N15-labeled recombinant protein (NP_001028675) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 22.4 kDa
• AA Sequence: MSFIFDWIYSGFSSVLQFLGLYKKT GKLVFLGLDNAGKTTLLHMLKDDRL GQHVPTLHPTSEELTIAGMTFTTFD LGGHVQARRVWKNYLPAINGIVFLV DCADHERLLESKEELDSLMTDETIA NVPILILGNKIDRPEAISEERLREM FGLYGQTTGKGSISLKELNARPLEV FMCSVLKRQGYGEGFRWMAQYIDTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SAR1B secretion associated Ras related GTPase 1B [ Homo sapiens (human) ]
• Official Symbol: SAR1B
• Synonyms: AR1B; SAR1 homolog B (S. cerevisiae); ANDD; CMRD; GTBPB; SARA2; GTP-binding protein SAR1b; 2310075M17Rik; SAR1a gene homolog 2; GTP-binding protein B; GTP-binding protein Sara; SAR1B; EC 3.6.5
• Gene ID: 51128
• mRNA Refseq: NM_001033503
• Protein Refseq: NP_001028675
• MIM: 607690
• UniProt ID: Q9Y6B6