Recombinant Human SCGB1A1 protein, His-tagged

• Cat.No.: SCGB1A1-3855H
• Product Overview: Recombinant Human SCGB1A1 protein(P11684)(Met1-Asn91), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human SCGB1A1 consists of 81 amino acids and migrates as a 9.2 kDa band as predicted in SDS-PAGE under reducing conditions.
• Protein length: Met1-Asn91
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 97 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Publication:
  Lung Secretoglobin Scgb1a1 Influences Alveolar Macrophage-Mediated Inflammation and Immunity (2020)

Gene Information

• Gene Name: SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) [ Homo sapiens ]
• Official Symbol: SCGB1A1
• Synonyms: SCGB1A1; secretoglobin, family 1A, member 1 (uteroglobin); UGB, uteroglobin; uteroglobin; CC10; CC16; CCSP; Uteroglobin (Clara cell specific 10 kD protein); blastokinin; urine protein 1; urinary protein 1; clara cells 10 kDa secretory protein; clara cell phospholipid-binding protein; UGB; UP1; UP-1; CCPBP
• Gene ID: 7356
• mRNA Refseq: NM_003357
• Protein Refseq: NP_003348
• MIM: 192020
• UniProt ID: P11684

Reviews

02/07/2022

Precise antibody validation, enhances our immunoprecipitation accuracy.

06/07/2019

Efficient protein purification, delivers high yield and purity consistently.

03/25/2019

Timely protein expression optimization, greatly boosts our research efforts.

Q&As

How does SCGB1A1 influence the response of lung tissue to environmental pollutants and allergens?

SCGB1A1 helps protect lung tissue from environmental pollutants and allergens, reducing the risk of damage and inflammation.

What are the mechanisms by which SCGB1A1 modulates immune cell recruitment and activation in the lungs?

SCGB1A1 influences immune cell behavior in the lungs, affecting responses to infections and inflammation.

How does SCGB1A1 (Secretoglobin Family 1A Member 1) function in respiratory tract defense and lung homeostasis?

SCGB1A1 is important for respiratory defense, contributing to the maintenance of lung health and protection against irritants.

What is the impact of SCGB1A1 in asthma and chronic obstructive pulmonary disease (COPD) pathogenesis?

SCGB1A1 is implicated in the pathogenesis of asthma and COPD, influencing airway inflammation and reactivity.

How do alterations in SCGB1A1 expression or function affect respiratory infections and healing after lung injury?

Changes in SCGB1A1 expression can impact the body's ability to fight respiratory infections and heal after lung injuries.

What role does SCGB1A1 play in modulating inflammatory responses in chronic lung diseases?

SCGB1A1 modulates inflammation in chronic lung conditions, potentially impacting disease progression.

How does SCGB1A1 contribute to mucus production and airway protection?

SCGB1A1 plays a role in mucus production, essential for trapping and clearing pathogens and particles from the airways.