Recombinant Human SCN4B Protein, MYC/DDK-tagged

• Cat.No.: SCN4B-461H
• Product Overview: Recombinant human SCN4B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 22 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: sodium voltage-gated channel beta subunit 4 [ Homo sapiens ]
• Official Symbol: SCN4B
• Synonyms: ATFB17; LQT10; Navbeta4
• Gene ID: 6330
• mRNA Refseq: NM_001142348.1
• Protein Refseq: NP_001135820.1
• MIM: 608256
• UniProt ID: Q8IWT1