Recombinant Human SELP protein, His-Avi-tagged, Biotinylated

• Cat.No.: SELP-109HB
• Product Overview: Recombinant biotinylated Human P-Selectin/CD62P Protein is expressed from mammalian with a poly-His and Avi tag at the C-terminal. It contains Trp 42-Ala 771.

Specification

• Description: Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells. A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a calculated MW of 82.9 kDa. Due to glycosylation, the protein migrates to 115- 140kDa based on Bis-Tris PAGE.
• Protein length: Trp 42-Ala 771
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: SELP
• Official Symbol: SELP
• Synonyms: CD62P antigen; CD62P; FLJ45155; GMP140; GRMP; PADGEM; PADGEMantigen CD62); PSEL; P-Selectin; selectin P (granule membrane protein 140kDa, antigen CD62); SELP
• Gene ID: 6403
• mRNA Refseq: NM_003005.4
• Protein Refseq: NP_002996.2
• MIM: 173610
• UniProt ID: P16109