| Description : |
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
90.7 kDa |
| AA Sequence : |
MGTPRAQHPPPPQLLFLILLSCPWI QGLPLKEEEILPEPGSETPTVASEA LAELLHGALLRRGPEMGYLPGPPLG PEGGEEETTTTIITTTTVTTTVTSP VLCNNNISEGEGYVESPDLGSPVSR TLGLLDCTYSIHVYPGYGIEIQVQT LNLSQEEELLVLAGGGSPGLAPRLL ANSSMLGEGQVLRSPTNRLLLHFQS PRVPRGGGFRIHYQAYLLSCGFPPR PAHGDVSVTDLHPGGTATFHCDSGY QLQGEETLICLNGTRPSWNGETPSC MASCGGTIHNATLGRIVSPEPGGAV GPNLTCRWVIEAAEGRRLHLHFERV SLDEDNDRLMVRSGGSPLSPVIYDS DMDDVPERGLISDAQSLYVELLSET PANPLLLSLRFEAFEEDRCFAPFLA HGNVTTTDPEYRPGALATFSCLPGY ALEPPGPPNAIECVDPTEPHWNDTE PACKAMCGGELSEPAGVVLSPDWPQ SYSPGQDCVWGVHVQEEKRILLQVE ILNVREGDMLTLFDGDGPSARVLAQ LRGPQPRRRLLSSGPDLTLQFQAPP GPPNPGLGQGFVLHFKEVPRNDTCP ELPPPEWGWRTASHGDLIRGTVLTY QCEPGYELLGSDILTCQWDLSWSAA PPACQKIMTCADPGEIANGHRTASD AGFPVGSHVQYRCLPGYSLEGAAML TCYSRDTGTPKWSDRVPKCALKYEP CLNPGVPENGYQTLYKHHYQAGESL RFFCYEGFELIGEVTITCVPGHPSQ WTSQPPLCKVTQTTDPSRQLEGGNL ALAILLPLGLVIVLGSGVYIYYTKL QGKSLFGFSGSHSYSPITVESDFSN PLYEAGDTREYEVSITRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
