Recombinant Human SH3BP5 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human SH3BP5 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : SH3BP5-1761H
Product Overview : SH3BP5 MS Standard C13 and N15-labeled recombinant protein (NP_004835) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25. Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 50.4 kDa
AA Sequence : MDAALKRSRS EEPAEILPPA RDEEEEEEEG MEQGLEEEEE VDPRIQGELE KLNQSTDDIN RRETELEDAR QKFRSVLVEA TVKLDELVKK IGKAVEDSKP YWEARRVARQ AQLEAQKATQ DFQRATEVLR AAKETISLAE QRLLEDDKRQ FDSAWQEMLN HATQRVMEAE QTKTRSELVH KETAARYNAA MGRMRQLEKK LKRAINKSKP YFELKAKYYV QLEQLKKTVD DLQAKLTLAK GEYKMALKNL EMISDEIHER RRSSAMGPRG CGVGAEGSST SVEDLPGSKP EPDAISVASE AFEDDSCSNF VSEDDSETQS VSSFSSGPTS PSEMPDQFPA VVRPGSLDLP SPVSLSEFGM MFPVLGPRSE CSGASSPECE VERGDRAEGA ENKTSDKANN NRGLSSSSGS GGSSKSQSST SPEGQALENR MKQLSLQCSK GRDGIIADIK MVQIGTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : SH3BP5 SH3 domain binding protein 5 [ Homo sapiens (human) ]
Official Symbol : SH3BP5
Synonyms : SH3BP5; SH3-domain binding protein 5 (BTK-associated); SH3 domain-binding protein 5; Sab; SH3 binding protein; SH3BP-5; SH3 domain-binding protein that preferentially associates with BTK; SAB;
Gene ID : 9467
mRNA Refseq : NM_004844
Protein Refseq : NP_004835
MIM : 605612
UniProt ID : O60239
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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