Recombinant Human SIAH2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SIAH2-2550H
• Product Overview: SIAH2 MS Standard C13 and N15-labeled recombinant protein (NP_005058) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.4 kDa
• AA Sequence: MSRPSSTGPSANKPCSKQPPPQPQH TPSPAAPPAAATISAAGPGSSAVPA AAAVISGPGGGGGAGPVSPQHHELT SLFECPVCFDYVLPPILQCQAGHLV CNQCRQKLSCCPTCRGALTPSIRNL AMEKVASAVLFPCKYATTGCSLTLH HTEKPEHEDICEYRPYSCPCPGASC KWQGSLEAVMSHLMHAHKSITTLQG EDIVFLATDINLPGAVDWVMMQSCF GHHFMLVLEKQEKYEGHQQFFAIVL LIGTRKQAENFAYRLELNGNRRRLT WEATPRSIHDGVAAAIMNSDCLVFD TAIAHLFADNGNLGINVTISTCCPT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SIAH2 siah E3 ubiquitin protein ligase 2 [ Homo sapiens (human) ]
• Official Symbol: SIAH2
• Synonyms: SIAH2; siah E3 ubiquitin protein ligase 2; seven in absentia (Drosophila) homolog 2, seven in absentia homolog 2 (Drosophila); E3 ubiquitin-protein ligase SIAH2; siah-2; seven in absentia homolog 2; hSiah2
• Gene ID: 6478
• mRNA Refseq: NM_005067
• Protein Refseq: NP_005058
• MIM: 602213
• UniProt ID: O43255