Recombinant Human SIL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SIL1-786H
• Product Overview: SIL1 MS Standard C13 and N15-labeled recombinant protein (NP_071909) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 48.8 kDa
• AA Sequence: MAPQSLPSSRMAPLGMLLGLLMAAC FTFCLSHQNLKEFALTNPEKSSTKE TERKETKAEEELDAEVLEVFHPTHE WQALQPGQAVPAGSHVRLNLQTGER EAKLQYEDKFRNNLKGKRLDINTNT YTSQDLKSALAKFKEGAEMESSKED KARQAEVKRLFRPIEELKKDFDELN VVIETDMQIMVRLINKFNSSSSSLE EKIAALFDLEYYVHQMDNAQDLLSF GGLQVVINGLNSTEPLVKEYAAFVL GAAFSSNPKVQVEAIEGGALQKLLV ILATEQPLTAKKKVLFALCSLLRHF PYAQRQFLKLGGLQVLRTLVQEKGT EVLAVRVVTLLYDLVTEKMFAEEEA ELTQEMSPEKLQQYRQVHLLPGLWE QGWCEITAHLLALPEHDAREKVLQT LGVLLTTCRDRYRQDPQLGRTLASL QAEYQVLASLELQDGEDEGYFQELL GSVNSLLKELRTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SIL1 SIL1 nucleotide exchange factor [ Homo sapiens (human) ]
• Official Symbol: SIL1
• Synonyms: SIL1; SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae); Marinesco Sjogren syndrome, MSS; nucleotide exchange factor SIL1; BAP; ULG5; BiP-associated protein; MSS
• Gene ID: 64374
• mRNA Refseq: NM_022464
• Protein Refseq: NP_071909
• MIM: 608005
• UniProt ID: Q9H173