Recombinant Human SIRT3 Protein, His-tagged
Cat.No. : | SIRT3-28H |
Product Overview : | Recombinant human SIRT3(101-399) protein with a N-terminal His-tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 37 kDa (theoretical); 33.5 kDa (observed) |
Protein length : | 101-399 |
Purity : | ≥60% estimated by SDS-PAGE |
Unit Definition : | One unit is defined as the amount of enzyme required to produce 1 nmole of 7-amino-4-methylcoumarin per minute at 25 centigrade in 50 mM Tris-HCl, pH 8.0, containing 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, 125 μM p53 amino acids 317-320 (Gln-Pro-Lys-Lys(e-acetyl)-AMC), and 6 mM NAD+. |
Stability : | ≥ 9 months |
Storage : | Store it at -80 centigrade |
Storage Buffer : | 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol |
Gene Name : | SIRT3 sirtuin 3 [ Homo sapiens (human) ] |
Official Symbol : | SIRT3 |
Synonyms : | SIRT3; sirtuin 3; SIR2L3; NAD-dependent protein deacetylase sirtuin-3, mitochondrial; NAD-dependent deacetylase sirtuin-3, mitochondrial; SIR2-like protein 3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase; regulatory protein SIR2 homolog 3; silent mating type information regulation 2, S.cerevisiae, homolog 3; sir2-like 3; sirtuin type 3 |
Gene ID : | 23410 |
mRNA Refseq : | NM_001017524 |
Protein Refseq : | NP_001017524 |
MIM : | 604481 |
UniProt ID : | Q9NTG7 |
Products Types
◆ Recombinant Protein | ||
SIRT3-0719H | Recombinant Human SIRT3 Protein (S118-K399), Tag Free | +Inquiry |
SIRT3-4060H | Recombinant Human SIRT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIRT3-0720H | Recombinant Human SIRT3 Protein (S118-K399), His/SUMO tagged | +Inquiry |
SIRT3-112H | Recombinant Human SIRT3 Protein, His-tagged | +Inquiry |
SIRT3-2747H | Recombinant Human Sirtuin 3, His-tagged | +Inquiry |
◆ Lysates | ||
SIRT3-1832HCL | Recombinant Human SIRT3 293 Cell Lysate | +Inquiry |
SIRT3-1833HCL | Recombinant Human SIRT3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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