Recombinant Human SLC14A1 Protein (E2-L389), 8×His-MBP, Flag tagged

• Cat.No.: SLC14A1-1344S
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-SLC14A1(E2-L389)-Flag Protein was expressed in Insect cell.

Specification

• Description: Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
• Source: Insect cell
• Species: Human
• Tag: 8His-MBP,Flag
• Form: Liquid
• Protein Length: E2-L389
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Formulation:
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) [ Homo sapiens (human) ]
• Official Symbol: SLC14A1
• Synonyms: SLC14A1; solute carrier family 14 (urea transporter), member 1 (Kidd blood group); JK; urea transporter 1; HsT1341; RACH1; RACH2; SLC14A1 JK; urea transporter-B1; urea transporter, erythrocyte; urea transporter JK glycoprotein; UT1; UTE; HUT11; UT-B1; FLJ33745; FLJ41687
• Gene ID: 6563
• mRNA Refseq: NM_001128588
• Protein Refseq: NP_001122060
• MIM: 613868
• UniProt ID: Q13336