Recombinant Human SLC17A5 protein, His & T7-tagged

• Cat.No.: SLC17A5-1206H
• Product Overview: Recombinant Human SLC17A5 aa. (Thr146~Phe405 (Accession # Q9NRA2) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.0kDa.
• Protein length: Thr146~Phe405 (Accession # Q9NRA2)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: SLC17A5 solute carrier family 17 member 5 [ Homo sapiens (human) ]
• Official Symbol: SLC17A5
• Synonyms: SLC17A5; solute carrier family 17 member 5; SD; AST; NSD; SLD; ISSD; SIASD; SIALIN; sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; membrane glycoprotein HP59; sialic acid storage disease; sodium/sialic acid cotransporter; solute carrier family 17 (acidic sugar transporter), member 5; solute carrier family 17 (anion/sugar transporter), member 5; vesicular H(+)/Aspartate-glutamate cotransporter
• Gene ID: 26503
• mRNA Refseq: NM_012434.4
• Protein Refseq: NP_036566.1
• UniProt ID: Q9NRA2