Recombinant Human SLC29A1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SLC29A1-3953H
• Product Overview: SLC29A1 MS Standard C13 and N15-labeled recombinant protein (NP_001071645) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50 kDa
• AA Sequence: MTTSHQPQDRYKAVWLIFFMLGLGT LLPWNFFMTATQYFTNRLDMSQNVS LVTAELSKDAQASAAPAAPLPERNS LSAIFNNVMTLCAMLPLLLFTYLNS FLHQRIPQSVRILGSLVAILLVFLI TAILVKVQLDALPFFVITMIKIVLI NSFGAILQGSLFGLAGLLPASYTAP IMSGQGLAGFFASVAMICAIASGSE LSESAFGYFITACAVIILTIICYLG LPRLEFYRYYQQLKLEGPGEQETKL DLISKGEEPRAGKEESGVSVSNSQP TNESHSIKAILKNISVLAFSVCFIF TITIGMFPAVTVEVKSSIAGSSTWE RYFIPVSCFLTFNIFDWLGRSLTAV FMWPGKDSRWLPSLVLARLVFVPLL LLCNIKPRRYLTVVFEHDAWFIFFM AAFAFSNGYLASLCMCFGPKKVKPA EAETAGAIMAFFLCLGLALGAVFSF LFRAIVTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SLC29A1 solute carrier family 29 member 1 (Augustine blood group) [ Homo sapiens (human) ]
• Official Symbol: SLC29A1
• Synonyms: SLC29A1; solute carrier family 29 (nucleoside transporters), member 1; ENT1; equilibrative nucleoside transporter 1; nucleoside transporter, es-type; solute carrier family 29 member 1; solute carrier family 29, member 1; equilibrative NBMPR-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter; MGC1465; MGC3778
• Gene ID: 2030
• mRNA Refseq: NM_001078177
• Protein Refseq: NP_001071645
• MIM: 602193
• UniProt ID: Q99808