Recombinant Human SLC30A10 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SLC30A10-5965H
• Product Overview: SLC30A10 MS Standard C13 and N15-labeled recombinant protein (NP_061183) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 52.5 kDa
• AA Sequence: MGRYSGKTCRLLFMLVLTVAFFVAE LVSGYLGNSIALLSDSFNMLSDLIS LCVGLSAGYIARRPTRGFSATYGYA RAEVVGALSNAVFLTALCFTIFVEA VLRLARPERIDDPELVLIVGVLGLL VNVVGLLIFQDCAAWFACCLRGRSR RLQQRQQLAEGCVPGAFGGPQGAED PRRAADPTAPGSDSAVTLRGTSVER KREKGATVFANVAGDSFNTQNEPED MMKKEKKSEALNIRGVLLHVMGDAL GSVVVVITAIIFYVLPLKSEDPCNW QCYIDPSLTVLMVIIILSSAFPLIK ETAAILLQMVPKGVNMEELMSKLSA VPGISSVHEVHIWELVSGKIIATLH IKYPKDRGYQDASTKIREIFHHAGI HNVTIQFENVDLKEPLEQKDLLLLC NSPCISKGCAKQLCCPPGALPLAHV NGCAEHNGGPSLDTYGSDGLSRRDA REVAIEVSLDSCLSDHGQSLNKTQE DQCYVNRTHFTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SLC30A10 solute carrier family 30 member 10 [ Homo sapiens (human) ]
• Official Symbol: SLC30A10
• Synonyms: SLC30A10; solute carrier family 30 member 10; ZNT8; ZRC1; HMDPC; ZNT10; ZnT-10; HMNDYT1; zinc transporter 10; manganese transporter SLC30A10; zinc transporter 8
• Gene ID: 55532
• mRNA Refseq: NM_018713
• Protein Refseq: NP_061183
• MIM: 611146
• UniProt ID: Q6XR72