Recombinant Human SLC8A1 Protein (396-627 aa), His-tagged
Cat.No. : | SLC8A1-2278H |
Product Overview : | Recombinant Human SLC8A1 Protein (396-627 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Mediates the exchange of one Ca2+ ion against three to four Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca2+ transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca2+ levels due to release of Ca2+ stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca2+ from the cell during the next phase, so that cytoplasmic Ca2+ levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 27.4 kDa |
Protein length : | 396-627 aa |
AA Sequence : | VNTEVTENDPVSKIFFEQGTYQCLE NCGTVALTIIRRGGDLTNTVFVDFR TEDGTANAGSDYEFTEGTVVFKPGD TQKEIRVGIIDDDIFEEDENFLVHL SNVKVSSEASEDGILEANHVSTLAC LGSPSTATVTIFDDDHAGIFTFEEP VTHVSESIGIMEVKVLRTSGARGNV IVPYKTIEGTARGGGEDFEDTCGEL EFQNDEIVKTISVKVIDDEEYEKNK TFFLEIG |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 [ Homo sapiens ] |
Official Symbol : | SLC8A1 |
Synonyms : | NCX1; |
Gene ID : | 6546 |
mRNA Refseq : | NM_021097.2 |
Protein Refseq : | NP_066920.1 |
MIM : | 182305 |
UniProt ID : | P32418 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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