Recombinant Human SLURP2 Protein (23-97 aa), His-tagged

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Recombinant Human SLURP2 Protein (23-97 aa), His-tagged

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Cat.No. : SLURP2-2440H
Product Overview : Recombinant Human SLURP2 Protein (23-97 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein.
Description : Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 10.0 kDa
Protein length : 23-97 aa
AA Sequence : IWCHQCTGFG GCSHGSRCLR DSTHCVTTAT RVLSNTEDLP LVTKMCHIGC PDIPSLGLGP YVSIACCQTS LCNHD
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : SLURP2 secreted LY6/PLAUR domain containing 2 [ Homo sapiens (human) ]
Official Symbol : SLURP2
Synonyms : SLURP2; SLURP-2;
Gene ID : 432355
mRNA Refseq : NM_177458
Protein Refseq : NP_803253
UniProt ID : P0DP57

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