Recombinant Human SLURP2 Protein (23-97 aa), His-tagged

• Cat.No.: SLURP2-2440H
• Product Overview: Recombinant Human SLURP2 Protein (23-97 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein.

Specification

• Description: Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 10.0 kDa
• Protein length: 23-97 aa
• AA Sequence: IWCHQCTGFGGCSHGSRCLRDSTHC VTTATRVLSNTEDLPLVTKMCHIGC PDIPSLGLGPYVSIACCQTSLCNHD
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: SLURP2 secreted LY6/PLAUR domain containing 2 [ Homo sapiens (human) ]
• Official Symbol: SLURP2
• Synonyms: SLURP2; SLURP-2
• Gene ID: 432355
• mRNA Refseq: NM_177458
• Protein Refseq: NP_803253
• UniProt ID: P0DP57