Recombinant Human SMPD3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SMPD3-6464H
• Product Overview: SMPD3 MS Standard C13 and N15-labeled recombinant protein (NP_061137) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: SMPD3 (Sphingomyelin Phosphodiesterase 3) is a Protein Coding gene. Diseases associated with SMPD3 include Pituitary Hormone Deficiency, Combined, 2 and Coffin-Siris Syndrome 1. Among its related pathways are Signaling by GPCR and NGF Pathway. Gene Ontology (GO) annotations related to this gene include sphingomyelin phosphodiesterase activity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 70.9 kDa
• AA Sequence: MVLYTTPFPNSCLSALHCVSWALIF PCYWLVDRLAASFIPTTYEKRQRAD DPCCLQLLCTALFTPIYLALLVASL PFAFLGFLFWSPLQSARRPYIYSRL EDKGLAGGAALLSEWKGTGPGKSFC FATANVCLLPDSLARVNNLFNTQAR AKEIGQRIRNGAARPQIKIYIDSPT NTSISAASFSSLVSPQGGDGVARAV PGSIKRTASVEYKGDGGRHPGDEAA NGPASGDPVDSSSPEDACIVRIGGE EGGRPPEADDPVPGGQARNGAGGGP RGQTPNHNQQDGDSGSLGSPSASRE SLVKGRAGPDTSASGEPGANSKLLY KASVVKKAAARRRRHPDEAFDHEVS AFFPANLDFLCLQEVFDKRAATKLK EQLHGYFEYILYDVGVYGCQGCCSF KCLNSGLLFASRYPIMDVAYHCYPN KCNDDALASKGALFLKVQVGSTPQD QRIVGYIACTHLHAPQEDSAIRCGQ LDLLQDWLADFRKSTSSSSAANPEE LVAFDVVCGDFNFDNCSSDDKLEQQ HSLFTHYRDPCRLGPGEEKPWAIGT LLDTNGLYDEDVCTPDNLQKVLESE EGRREYLAFPTSKSSGQKGRKELLK GNGRRIDYMLHAEEGLCPDWKAEVE EFSFITQLSGLTDHLPVAMRLMVSS GEEEATRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SMPD3 sphingomyelin phosphodiesterase 3 [ Homo sapiens (human) ]
• Official Symbol: SMPD3
• Synonyms: SMPD3; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II); sphingomyelin phosphodiesterase 3; NSMASE2; nSMase-2; neutral sphingomyelinase 2; neutral sphingomyelinase II; FLJ22593; MGC138443
• Gene ID: 55512
• mRNA Refseq: NM_018667
• Protein Refseq: NP_061137
• MIM: 605777
• UniProt ID: Q9NY59