"SMYD2" Related Products


Recombinant Human SMYD2 protein, GST-tagged

Cat.No.: SMYD2-262H
Product Overview: Recombinant Human SMYD2 fused with GST tag at N-terminal was expressed in E. coli.
Description: SMYD2 is a lysine mono-methyltransferase that has been shown to have activity on histone H3, p53 (Lys370), pRB (Lys380) and HSP90 (Lys616). The SMYD2 locus is amplified in lung carcinoma, serous ovarian carcinoma, and pancreatic ductal adenocarcinoma. SMYD2 expression is linked to a variety of cancers. Elevated levels of SMYD2 in esophageal squamous cell carcinoma patients are correlated with lower rates of survival.
Source: E. coli
Species: Human
Tag : GST
Form: In 100mM Tris pH 8.0, 10 mM glutathione and 10% glycerol.
Molecular Mass: 68 kDa
Applications: Recombinant SMYD2, human is useful for histone H3 methylation experiments, enzyme kinetics and inhibitor screening. Use of 1-3 µg SMYD2 per reaction with recombinant histone H3 as a substrate is recommended.
Storage: Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration: 1 µg/µl
Gene Name: SMYD2 SET and MYND domain containing 2 [ Homo sapiens ]
Official Symbol: SMYD2
Synonyms: SMYD2; SET and MYND domain containing 2; N-lysine methyltransferase SMYD2; HSKM B; KMT3C; ZMYND14; lysine N-methyltransferase 3C; histone methyltransferase SMYD2; zinc finger, MYND domain containing 14; SET and MYND domain-containing protein 2; HSKM-B; MGC119305;
Gene ID: 56950
mRNA Refseq: NM_020197
Protein Refseq: NP_064582
MIM: 610663
UniProt ID: Q9NRG4
Chromosome Location: 1q32.3
Pathway: p53 pathway, organism-specific biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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