Recombinant Full Length Human SNAP25 Protein, His tagged

• Cat.No.: SNAP25-296H
• Product Overview: Recombinant Full Length Human SNAP25 Protein with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-206 aa
• Description: Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
• Molecular Mass: 24.6 kDa
• AASequence: MGSSHHHHHHSSGLVPRGSHMAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQ
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50mM HEPES buffer (pH 7.4) containing 5mM DTT, 100mM NaCl
• Concentration: 1.26 mg/mL by Bradford
• Publications:
  Antigen Detection via the Rate of Ion Current Rectification Change of the Antibody-Modified Glass Nanopore Membrane. (2014)

Gene Information

• Gene Name: SNAP25 synaptosomal-associated protein, 25kDa [ Homo sapiens (human) ]
• Official Symbol: SNAP25
• Synonyms: SNAP25; synaptosomal-associated protein, 25kDa; SNAP, synaptosomal associated protein, 25kD; synaptosomal-associated protein 25; bA416N4.2; dJ1068F16.2; resistance to inhibitors of cholinesterase 4 homolog; RIC 4; RIC4; SEC9; SNAP 25; SUP; super protein; SNAP; RIC-4; SNAP-25; FLJ23079
• Gene ID: 6616
• mRNA Refseq: NM_003081
• Protein Refseq: NP_003072
• MIM: 600322
• UniProt ID: P60880