Recombinant Human SNX5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SNX5-6635H
• Product Overview: SNX5 MS Standard C13 and N15-labeled recombinant protein (NP_689413) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.8 kDa
• AA Sequence: MAAVPELLQQQEEDRSKLRSVSVDL NVDPSLQIDIPDALSERDKVKFTVH TKTTLPTFQSPEFSVTRQHEDFVWL HDTLIETTDYAGLIIPPAPTKPDFD GPREKMQKLGEGEGSMTKEEFAKMK QELEAEYLAVFKKTVSSHEVFLQRL SSHPVLSKDRNFHVFLEYDQDLSVR RKNTKEMFGGFFKSVVKSADEVLFT GVKEVDDFFEQEKNFLINYYNRIKD SCVKADKMTRSHKNVADDYIHTAAC LHSLALEEPTVIKKYLLKVAELFEK LRKVEGRVSSDEDLKLTELLRYYML NIEAAKDLLYRRTKALIDYENSNKA LDKARLKSKDVKLAEAHQQECCQKF EQLSESAKEELINFKRKRVAAFRKN LIEMSELEIKHARNNVSLLQSCIDL FKNNTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SNX5 sorting nexin 5 [ Homo sapiens (human) ]
• Official Symbol: SNX5
• Synonyms: SNX5; sorting nexin 5; sorting nexin-5; FLJ10931
• Gene ID: 27131
• mRNA Refseq: NM_152227
• Protein Refseq: NP_689413
• MIM: 605937
• UniProt ID: Q9Y5X3