Recombinant Human SPINT2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SPINT2-3247H
• Product Overview: SPINT2 MS Standard C13 and N15-labeled recombinant protein (NP_066925) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 28.2 kDa
• AA Sequence: MAQLCGLRRSRAFLALLGSLLLSGV LAADRERSIHDFCLVSKVVGRCRAS MPRWWYNVTDGSCQLFVYGGCDGNS NNYLTKEECLKKCATVTENATGDLA TSRNAADSSVPSAPRRQDSEDHSSD MFNYEEYCTANAVTGPCRASFPRWY FDVERNSCNNFIYGGCRGNKNSYRS EEACMLRCFRQQENPPLPLGSKVVL LAGLFVMVLILFLGASMVYLIRVAR RNQERALRTVWSSGDDKEQLVKNTY VLTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SPINT2 serine peptidase inhibitor, Kunitz type 2 [ Homo sapiens (human) ]
• Official Symbol: SPINT2
• Synonyms: SPINT2; serine peptidase inhibitor, Kunitz type, 2; serine protease inhibitor, Kunitz type, 2; kunitz-type protease inhibitor 2; HAI 2; Kop; placental bikunin; hepatocyte growth factor activator inhibitor type 2; PB; HAI2; DIAR3; HAI-2; FLJ45571
• Gene ID: 10653
• mRNA Refseq: NM_021102
• Protein Refseq: NP_066925
• MIM: 605124
• UniProt ID: O43291