| Description : |
The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
124.3 kDa |
| AA Sequence : |
MSTPSRFKKDKEIIAEYESQVKEIR AQLVEQQKCLEQQTEMRVQLLQDLQ DFFRKKAEIETEYSRNLEKLAERFM AKTRSTKDHQQYKKDQNLLSPVNCW YLLLNQVRRESKDHATLSDIYLNNV IMRFMQISEDSTRMFKKSKEIAFQL HEDLMKVLNELYTVMKTYHMYHAES ISAESKLKEAEKQEEKQIGRSGDPV FHIRLEERHQRRSSVKKIEKMKEKR QAKYSENKLKSIKARNEYLLTLEAT NASVFKYYIHDLSDLIDCCDLGYHA SLNRALRTYLSAEYNLETSRHEGLD IIENAVDNLEPRSDKQRFMEMYPAA FCPPMKFEFQSHMGDEVCQVSAQQP VQAELMLRYQQLQSRLATLKIENEE VKKTTEATLQTIQDMVTIEDYDVSE CFQHSRSTESVKSTVSETYLSKPSI AKRRANQQETEQFYFMKLREYLEGS NLITKLQAKHDLLQRTLGEGHRAEY MTTRPPNVPPKPQKHRKSRPRSQYN TKLFNGDLETFVKDSGQVIPLIVES CIRFINLYGLQHQGIFRVSGSQVEV NDIKNSFERGENPLADDQSNHDINS VAGVLKLYFRGLENPLFPKERFNDL ISCIRIDNLYERALHIRKLLLTLPR SVLIVMRYLFAFLNHLSQYSDENMM DPYNLAICFGPTLMPVPEIQDQVSC QAHVNEIIKTIIIHHETIFPDAKEL DGPVYEKCMAGDDYCDSPYSEHGTL EEVDQDAGTEPHTSEDECEPIEAIA KFDYVGRSARELSFKKGASLLLYHR ASEDWWEGRHNGIDGLVPHQYIVVQ DMDDTFSDTLSQKADSEASSGPVTE DKSSSKDMNSPTDRHPDGYLARQRK RGEPPPPVRRPGRTSDGHCPLHPPH ALSNSSVDLGSPSLASHPRGLLQNR GLNNDSPERRRRPGHGSLTNISRHD SLKKIDSPPIRRSTSSGQYTGFNDH KPLDPETIAQDIEETMNTALNELRE LERQSTAKHAPDVVLDTLEQVKNSP TPATSTESLSPLHNVALRSSEPQIR RSTSSSSDTMSTFKPMVAPRMGVQL KPPALRPKPAVLPKTNPTIGPAPPP QGPTDKSCTMTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
