Species : |
Human |
Source : |
HEK293 |
Tag : |
His |
Description : |
LowDensity Lipoprotein ReceptorRelated Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDLreceptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor. |
Form : |
Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2 |
AA Sequence : |
EHSENVHISG VSTACGETPE QIRAPSGIIT SPGWPSEYPA KINCSWFIRA NPGEIITISF QDFDIQGSR RCNLDWLTIE TYKNIESYRA CGSTIPPPYI SSQDHIWIRF HSDDNISRKG F RLAYFSGK SEEPNCACDQ FRCGNGKCIP EAWKCNNMDE CGDSSDEEIC AKEANPPTAA AF QPCAYNQ FQCLSRFTKV YTCLPESLKC DGNIDCLDLG DEIDCDVPTC GQWLKYFYGT FNS PNYPDF YPPGSNCTWL |
Purity : |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Notes : |
For research use only. |
Storage : |
Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months. |