| Description : |
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
124.8 kDa |
| AA Sequence : |
MFSQVPRTPASGCYYLNSMTPEGQE MYLRFDQTTRRSPYRMSRILARHQL VTKIQQEIEAKEACDWLRAAGFPQY AQLYEDSQFPINIVAVKNDHDFLEK DLVEPLCRRLNTLNKCASMKLDVNF QRKKGDDSDEEDLCISNKWTFQRTS RRWSRVDDLYTLLPRGDRNGSPGGT GMRNTTSSESVLTDLSEPEVCSIHS ESSGGSDSRSQPGQCCTDNPVMLDA PLVSSSLPQPPRDVLNHPFHPKNEK PTRARAKSFLKRMETLRGKGAHGRH KGSGRTGGLVISGPMLQQEPESFKA MQCIQIPNGDLQNSPPPACRKGLPC SGKSSGESSPSEHSSSGVSTPCLKE RKCHEANKRGGMYLEDLDVLAGTAL PDAGDQSRMHEFHSQENLVVHIPKD HKPGTFPKALSIESLSPTDSSNGVN WRTGSISLGREQVPGAREPRLMASC HRASRVSIYDNVPGSHLYASTGDLL DLEKDDLFPHLDDILQHVNGLQEVV DDWSKDVLPELQTHDTLVGEPGLST FPSPNQITLDFEGNSVSEGRTTPSD VERDVTSLNESEPPGVRDRRDSGVG ASLTRPNRRLRWNSFQLSHQPRPAP ASPHISSQTASQLSLLQRFSLLRLT AIMEKHSMSNKHGWTWSVPKFMKRM KVPDYKDKAVFGVPLIVHVQRTGQP LPQSIQQALRYLRSNCLDQVGLFRK SGVKSRIHALRQMNENFPENVNYED QSAYDVADMVKQFFRDLPEPLFTNK LSETFLHIYQYVSKEQRLQAVQAAI LLLADENREVLQTLLCFLNDVVNLV EENQMTPMNLAVCLAPSLFHLNLLK KESSPRVIQKKYATGKPDQKDLNEN LAAAQGLAHMIMECDRLFEVPHELV AQSRNSYVEAEIHVPTLEELGTQLE ESGATFHTYLNHLIQGLQKEAKEKF KGWVTCSSTDNTDLAFKKVGDGNPL KLWKASVEVEAPPSVVLNRVLRERH LWDEDFVQWKVVETLDRQTEIYQYV LNSMAPHPSRDFVVLRTWKTDLPKG MCTLVSLSVEHEEAQLLGGVRAVVM DSQYLIEPCGSGKSRLTHICRIDLK GHSPEWYSKGFGHLCAAEVARIRNS FQPLIAEGPETKITRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
