Recombinant Human STING1 Protein, His-tagged

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Recombinant Human STING1 Protein, His-tagged

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Cat.No. : STING1-006H
Product Overview : Recombinant human STING R232, G230A, R293Q mutant (138-379, N-terminal truncation) with a N-terminal histidine-tag was purified from E. coli.
Description : This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His
Form : 50 mM HEPES, pH 8.0, 150 mM sodium chloride, and 10%
Molecular Mass : 28.8 kDa
Protein length : 138-379
Purity : ≥80% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : Store at -80 centigrade
Shipping : Dry ice in continental US; may vary elsewhere
SDS-PAGE analysis of STING1. :

Lane 1: MW Markers
Lane 2: STING1 variant (1 µg)
Lane 3: STING1 variant (2 µg)
Lane 4: STING1 variant (4 µg)

Gene Name : STING1 stimulator of interferon response cGAMP interactor 1 [ Homo sapiens (human) ]
Official Symbol : STING1
Synonyms : STING1; stimulator of interferon response cGAMP interactor 1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation;stimulator of interferon protein;transmembrane protein 173
Gene ID : 340061
mRNA Refseq : NM_001301738
Protein Refseq : NP_001288667
MIM : 612374
UniProt ID : V5V0K2
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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