- Human(4)
Recombinant Human STING1 Protein, His-tagged
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| Cat.No. : | STING1-024H |
| Product Overview : | Recombinant Human STING H232 variant (138-379, N-terminal truncation) with a N-terminal His tag was expressed in E. coli. |
| Description : | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | 50 mM HEPES, pH 8.0, 150 mM sodium chloride, 10% glycerol |
| Molecular Mass : | 28.8 kDa |
| Protein length : | 138-379 |
| Purity : | ≥70% estimated by SDS-PAGE |
| Stability : | ≥ 1 year |
| Storage : | Store at -80 centigrade |
| Shipping : | Dry ice in continental US; may vary elsewhere |
| SDS-PAGE analysis of STING1. : |
Lane 1: MW Markers |
| Gene Name : | STING1 stimulator of interferon response cGAMP interactor 1 [ Homo sapiens (human) ] |
| Official Symbol : | STING1 |
| Synonyms : | STING1; stimulator of interferon response cGAMP interactor 1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation; stimulator of interferon protein; transmembrane protein 173 |
| Gene ID : | 340061 |
| mRNA Refseq : | NM_198282 |
| Protein Refseq : | NP_938023 |
| MIM : | 612374 |
| UniProt ID : | Q86WV6 |
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