Recombinant Human SUV420H1, GST-tagged

• Cat.No.: SUV420H1-473H
• Product Overview: Recombinant Human SUV420H1, amino acids 2-387 with N-terminal GST tag expressed inE.Coliexpression system. MW = 70kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 2-387 a.a.
• Description: Histone-lysine N-methyltransferase SUV420H1 is an enzyme that in humans is encoded by the SUV420H1 gene.This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene.
• Purity: >20%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) [ Homo sapiens ]
• Synonyms: SUV420H1; suppressor of variegation 4-20 homolog 1 (Drosophila); CGI85; KMT5B; CGI-85; MGC703; MGC21161; MGC118906; MGC118909; OTTHUMP00000197482; OTTHUMP00000197488; C630029K18Rik; EC 2.1.1.43
• Gene ID: 51111
• mRNA Refseq: NM_016028
• Protein Refseq: NP_057112
• MIM: 610881
• UniProt ID: Q4FZB7
• Chromosome Location: 11q13.2
• Pathway: Lysine degradation
• Function: histone methyltransferase activity (H4-K20 specific); protein binding; transferase activity