Recombinant Human SYT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SYT1-2918H
• Product Overview: SYT1 MS Standard C13 and N15-labeled recombinant protein (NP_001129277) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.4 kDa
• AA Sequence: MVSESHHEALAAPPVTTVATVLPSN ATEPASPGEGKEDAFSKLKEKFMNE LHKIPLPPWALIAIAIVAVLLVLTC CFCICKKCLFKKKNKKKGKEKGGKN AINMKDVKDLGKTMKDQALKDDDAE TGLTDGEEKEEPKEEEKLGKLQYSL DYDFQNNQLLVGIIQAAELPALDMG GTSDPYVKVFLLPDKKKKFETKVHR KTLNPVFNEQFTFKVPYSELGGKTL VMAVYDFDRFSKHDIIGEFKVPMNT VDFGHVTEEWRDLQSAEKEEQEKLG DICFSLRYVPTAGKLTVVILEAKNL KKMDVGGLSDPYVKIHLMQNGKRLK KKKTTIKKNTLNPYYNESFSFEVPF EQIQKVQVVVTVLDYDKIGKNDAIG KVFVGYNSTGAELRHWSDMLANPRR PIAQWHTLQVEEEVDAMLAVKKTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SYT1 synaptotagmin I [ Homo sapiens (human) ]
• Official Symbol: SYT1
• Synonyms: SYT1; synaptotagmin I; SVP65, SYT; synaptotagmin-1; P65; sytI; synaptotagmin 1; SYT; SVP65; DKFZp781D2042
• Gene ID: 6857
• mRNA Refseq: NM_001135805
• Protein Refseq: NP_001129277
• MIM: 185605
• UniProt ID: P21579