| Description : |
This gene encodes a protein with a conserved domain, referred to as the TBC domain, characteristic of proteins which interact with GTPases. TBC domain proteins may serve as GTPase-activating proteins for a particular group of GTPases, the Rab (Ras-related proteins in brain) small GTPases which are involved in the regulation of membrane trafficking. Mutations in this gene are associated with familial infantile myoclonic epilepsy. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
62.3 kDa |
| AA Sequence : |
MDSPGYNCFVDKDKMDAAIQDLGPK ELSCTELQELKQLARQGYWAQSHAL RGKVYQRLIRDIPCRTVTPDASVYS DIVGKIVGKHSSSCLPLPEFVDNTQ VPSYCLNARGEGAVRKILLCLANQF PDISFCPALPAVVALLLHYSIDEAE CFEKACRILACNDPGRRLIDQSFLA FESSCMTFGDLVNKYCQAAHKLMVA VSEDVLQVYADWQRWLFGELPLCYF ARVFDVFLVEGYKVLYRVALAILKF FHKVRAGQPLESDSVKQDIRTFVRD IAKTVSPEKLLEKAFAIRLFSRKEI QLLQMANEKALKQKGITVKQKRQFV HLAVHAENFRSEIVSVREMRDIWSW VPERFALCQPLLLFSSLQHGYSLAR FYFQCEGHEPTLLLIKTTQKEVCGA YLSTDWSERNKFGGKLGFFGTGECF VFRLQPEVQRYEWVVIKHPELTKPP PLMAAEPTAPLSHSASSDPADRLSP FLAARHFNLPSKTESMFMAGGSDCL IVGGGGGQALYIDGDLNRGRTSHCD TFNNQPLCSENFLIAAVEAWGFQDP DTQTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
