| Description : |
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.3 kDa |
| AA Sequence : |
MSDTLTADVIGRRVEVNGEHATVRF AGVVPPVAGPWLGVEWDNPERGKHD GSHEGTVYFKCRHPTGGSFIRPNKV NFGTDFLTAIKNRYVLEDGPEEDRK EQIVTIGNKPVETIGFDSIMKQQSQ LSKLQEVSLRNCAVSCAGEKGGVAE ACPNIRKVDLSKNLLSSWDEVIHIA DQLRHLEVLNVSENKLKFPSGSVLT GTLSVLKVLVLNQTGITWAEVLRCV AGCPGLEELYLESNNIFISERPTDV LQTVKLLDLSSNQLIDENQLYLIAH LPRLEQLILSDTGISSLHFPDAGIG CKTSMFPSLKYLVVNDNQISQWSFF NELEKLPSLRALSCLRNPLTKEDKE AETARLLIIASIGQLKTLNKCEILP EERRRAELDYRKAFGNEWKQAGGHK DPEKNRLSEEFLTAHPRYQFLCLKY GAPEDWELKTQQPLMLKNQLLTLKI KYPHQLDQKVLEKQLPGSMTIQKVK GLLSRLLKVPVSDLLLSYESPKKPG REIELENDLKSLQFYSVENGDCLLV RWTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
