Recombinant Human TCEB2 protein

Species :	Human
Source :	E.coli
Tag :	Non
Protein Length :	1-118 aa
Description :	Elongin B , also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant TCEB2 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Form :	Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.1 mM PMSF, 20% glycerol.
Molecular Mass :	13.1 kDa
AA Sequence :	MDVFLMIRRH KTTIFTDAKE SSTVFELKRI VEGILKRPPD EQRLYKDDQL LDDGKTLGEC GFTSQTARPQ APATVGLAFR ADDTFEALCI EPFSSPPELP DVMKPQDSGS SANEQAVQ
Purity :	> 95% by SDS - PAGE
Notes :	For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage :	Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration :	1 mg/ml (determined by Bradford assay)

Gene Name	TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) [ Homo sapiens ]
Official Symbol	TCEB2
Synonyms	Elongin B; TCEB2; SIII p18; EloB; Elongin 18 kDa subunit; EloB; TCEB 2;
Gene ID	6923
mRNA Refseq	NM_007108
Protein Refseq	NP_009039
MIM	600787
UniProt ID	Q15370