Recombinant Human TES Protein, MYC/DDK-tagged

Species :	Human
Source :	HEK293
Tag :	DDK&Myc
Description :	Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011].
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass :	47.8 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name	testin LIM domain protein[ Homo sapiens ]
Official Symbol	TES
Synonyms	TESS; TESS-2
Gene ID	26136
mRNA Refseq	NM_015641.2
Protein Refseq	NP_056456.1
MIM	606085
UniProt ID	Q9UGI8