Recombinant Human TFIP11 Protein, MYC/DDK-tagged

• Cat.No.: TFIP11-557H
• Product Overview: Recombinant human TFIP11 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 96.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: tuftelin interacting protein 11[ Homo sapiens ]
• Official Symbol: TFIP11
• Synonyms: bK445C9.6; hNtr1; NTR1; Spp382; TIP39
• Gene ID: 24144
• mRNA Refseq: NM_001008697.1
• Protein Refseq: NP_001008697.1
• MIM: 612747
• UniProt ID: Q9UBB9