Recombinant Human Thy1 Protein, Fc-tagged

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Recombinant Human Thy1 Protein, Fc-tagged

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Cat.No. : THY1-541H
Product Overview : Recombinant Human THY1 (NP_006279.2) (Met1-Cys130) was expressed with the Fc region of human IgG1 at the C-terminus.
Description : Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thym centigradeytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.
Source : HEK293
Species : Human
Tag : Fc
Predicted N Terminal : Gln 20
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human THY1 consists of 349 amino acids and predicts a molecular mass of 39.3 kDa
Protein length : Met1-Cys130
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : THY1 Thy-1 cell surface antigen [ Homo sapiens ]
Official Symbol : THY1
Synonyms : THY1; Thy-1 cell surface antigen; thy-1 membrane glycoprotein; CD90; CDw90; thy-1 antigen; Thy-1 T-cell antigen; FLJ33325;
Gene ID : 7070
mRNA Refseq : NM_006288
Protein Refseq : NP_006279
MIM : 188230
UniProt ID : P04216
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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