| Description : |
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
70.6 kDa |
| AA Sequence : |
MEGPRENQDPPPRPLARHLSDADRL RKVIQELVDTEKSYVKDLSCLFELY LEPLQNETFLTQDEMESLFGSLPEM LEFQKVFLETLEDGISASSDFNTLE TPSQFRKLLFSLGGSFLYYADHFKL YSGFCANHIKVQKVLERAKTDKAFK AFLDARNPTKQHSSTLESYLIKPVQ RVLKYPLLLKELVSLTDQESEEHYH LTEALKAMEKVASHINEMQKIYEDY GTVFDQLVAEQSGTEKEVTELSMGE LLMHSTVSWLNPFLSLGKARKDLEL TVFVFKRAVILVYKENCKLKKKLPS NSRPAHNSTDLDPFKFRWLIPISAL QVRLGNPAGTENNSIWELIHTKSEI EGRPETIFQLCCSDSESKTNIVKVI RSILRENFRRHIKCELPLEKTCKDR LVPLKNRVPVSAKLASSRSLKVLKN SSSNEWTGETGKGTLLDSDEGSLSS GTQSSGCPTAEGRQDSKSTSPGKYP HPGLADFADNLIKESDILSDEDDDH RQTVKQGSPTKDIEIQFQRLRISED PDVHPEAEQQPGPESGEGQKGGEQP KLVRGHFCPIKRKANSTKRDRGTLL KAQIRHQSLDSQSENATIDLNSVLE REFSVQSLTSVVSEECFYETESHGK STRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
