Recombinant Human TIE1 Protein, hIgG/His-tagged
Cat.No. : | TIE1-01H |
Product Overview : | Recombinant human Tie-1 (22-759aa, 977aa), fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
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- Gene Information
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Description : | This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | hIgG-His |
Form : | Liquid |
Molecular Mass : | 106.8 kDa |
AA Sequence : | AVDLTLLANLRLTDPQRFFLTCVSG EAGAGRGSDAWGPPLLLEKDDRIVR TPPGPPLRLARNGSHQVTLRGFSKP SDLVGVFSCVGGAGARRTRVIYVHN SPGAHLLPDKVTHTVNKGDTAVLSA RVHKEKQTDVIWKSNGSYFYTLDWH EAQDGRFLLQLPNVQPPSSGIYSAT YLEASPLGSAFFRLIVRGCGAGRWG PGCTKECPGCLHGGVCHDHDGECVC PPGFTGTRCEQACREGRFGQSCQEQ CPGISGCRGLTFCLPDPYGCSCGSG WRGSQCQEACAPGHFGADCRLQCQC QNGGTCDRFSGCVCPSGWHGVHCEK SDRIPQILNMASELEFNLETMPRIN CAAAGNPFPVRGSIELRKPDGTVLL STKAIVEPEKTTAEFEVPRLVLADS GFWECRVSTSGGQDSRRFKVNVKVP PVPLAAPRLLTKQSRQLVVSPLVSF SGDGPISTVRLHYRPQDSTMDWSTI VVDPSENVTLMNLRPKTGYSVRVQL SRPGEGGEGAWGPPTLMTTDCPEPL LQPWLEGWHVEGTDRLRVSWSLPLV PGPLVGDGFLLRLWDGTRGQERREN VSSPQARTALLTGLTPGTHYQLDVQ LYHCTLLGPASPPAHVLLPPSGPPA PRHLHAQALSDSEIQLTWKHPEALP GPISKYVVEVQVAGGAGDPLWIDVD RPEETSTIIRGLNASTRYLFRMRAS IQGLGDWSNTVEESTLGNGLQAEGP VQESRAAEEGLDQ |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by Absorbance at 280nm) |
Storage Buffer : | 20mM Tris-HCl (pH 8.0) containing 0.1M NaCl, 50% glycerol |
Gene Name : | TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 [ Homo sapiens (human) ] |
Official Symbol : | TIE1 |
Synonyms : | TIE1; tyrosine kinase with immunoglobulin like and EGF like domains 1; TIE; JTK14; LMPHM11; tyrosine-protein kinase receptor Tie-1; tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; EC 2.7.10.1 |
Gene ID : | 7075 |
mRNA Refseq : | NM_005424 |
Protein Refseq : | NP_005415 |
MIM : | 600222 |
UniProt ID : | P35590 |
Products Types
◆ Recombinant Protein | ||
TIE1-9210M | Recombinant Mouse TIE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TIE1-1256H | Recombinant Human TIE1 Protein, His-tagged | +Inquiry |
Tie1-6427M | Recombinant Mouse Tie1 Protein, Myc/DDK-tagged | +Inquiry |
TIE1-1255H | Recombinant Human TIE1 Protein, His-tagged | +Inquiry |
TIE1-144H | Recombinant Human TIE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TIE1-2034HCL | Recombinant Human TIE1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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