Recombinant Human TIRAP Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | TIRAP-5577H |
Product Overview : | TIRAP MS Standard C13 and N15-labeled recombinant protein (NP_001034750) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 28 kDa |
AA Sequence : | MASSTSLPAPGSRPKKPLGKMADWF RQTLLKKPKKRPNSPESTSSDASQP TSQDSPLPPSLSSVTSPSLPPTHAS DSGSSRWSKDYDVCVCHSEEDLVAA QDLVSYLEGSTASLRCFLQLRDATP GGAIVSELCQALSSSHCRVLLITPG FLQDPWCKYQMLQALTEAPGAEGCT IPLLSGLSRAAYPPELRFMYYVDGR GPDGGFRQVKEAVMRYLQTLSWHLL YHGTPEIGVKLETENPCRASDSHKC DKRYRETRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | TIRAP TIR domain containing adaptor protein [ Homo sapiens (human) ] |
Official Symbol : | TIRAP |
Synonyms : | TIRAP; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Toll interleukin 1 receptor (TIR) domain containing adaptor protein; toll/interleukin-1 receptor domain-containing adapter protein; Mal; MyD88 adapter like; wyatt; adapter protein wyatt; adaptor protein Wyatt; MyD88 adapter-like protein; Toll-like receptor adaptor protein; BACTS1; FLJ42305; |
Gene ID : | 114609 |
mRNA Refseq : | NM_001039661 |
Protein Refseq : | NP_001034750 |
MIM : | 606252 |
UniProt ID : | P58753 |
Products Types
◆ Recombinant Protein | ||
Tirap-595M | Recombinant Mouse Tirap Protein, MYC/DDK-tagged | +Inquiry |
TIRAP-4539R | Recombinant Rhesus Macaque TIRAP Protein, His (Fc)-Avi-tagged | +Inquiry |
TIRAP-1117H | Recombinant Human TIRAP Protein, MYC/DDK-tagged | +Inquiry |
TIRAP-768C | Recombinant Cynomolgus Monkey TIRAP Protein, His (Fc)-Avi-tagged | +Inquiry |
TIRAP-2798H | Recombinant Human TIRAP protein, His-tagged | +Inquiry |
◆ Lysates | ||
TIRAP-1782HCL | Recombinant Human TIRAP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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