"TK2" Related Products

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Recombinant Human TK2 Protein, His-tagged

Cat.No. : TK2-914H
Product Overview : Recombinant Human TK2, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.
Description : This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria.
Source : E. coli
Tag : His
Form : 50mM Tris, 8M Urea, pH8.0.
Molecular Mass : 27.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TK2 thymidine kinase 2, mitochondrial [ Homo sapiens ]
Official Symbol : TK2
Synonyms : TK2; thymidine kinase 2, mitochondrial; mt-TK; MTTK; MTDPS2;
Gene ID : 7084
mRNA Refseq : NM_001172643
Protein Refseq : NP_001166114
MIM : 188250
UniProt ID : O00142

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