| Description : |
The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
65.4 kDa |
| AA Sequence : |
MADAEARAEFPEEARPDRGTLQVFQ DMASRLRIHSIRATCSTSSGHPTSC SSSSEIMSVLFFYIMRYKQSDPENP DNDRFVLAKRLSFVDVATGWLGQGL GVACGMAYTGKYFDRASYRVFCLMS DGESSEGSVWEAMAFASYYSLDNLV ATFDVNRLGHSGALPAEHCINIYQR RCEAFGWNTYVVDGRDVEALCQVFW QASQVKHKPTAVVAKTFKGRGTPSI EDAESWHAKPMPRERADAIIKLIES QIQTSRNLDPQPPIEDSPEVNITDV RMTSPPDYRVGDKIATRKACGLALA KLGYANNRVVVLDGDTRYSTFSEIF NKEYPERFIECFMAEQNMVSVALGC ASRGRTIAFASTFAAFLTRAFDHIR IGGLAESNINIIGSHCGVSVGDDGA SQMALEDIAMFRTIPKCTIFYPTDA VSTEHAVALAANAKGMCFIRTTRPE TMVIYTPQERFEIGQAKVLRHCVSD KVTVIGAGITVYEALAAADELSKQD IFIRVIDLFTIKPLDVATIVSSAKA TEGRIITVEDHYPQGGIGEAVCAAV SMDPDIQVHSLAVSGVPQSGKSEEL LDMYGISARHIIVAVKCMLLNTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
