Recombinant Human TNFSF18 Protein (Gln72-Ser199), HIgG1 Fc-tagged

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Recombinant Human TNFSF18 Protein (Gln72-Ser199), HIgG1 Fc-tagged

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Cat.No. : TNFSF18-641H
Product Overview : Recombinant Human TNFSF18 Protein (NP_005083.2) (Gln72-Ser199) was produced by HEK293 Cells expression system. This protein was expressed with the Fc region of human IgG1 at the C-terminus.
Description : The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Source : HEK293
Species : Human
Tag : HIgG1 Fc
Predicted N Terminal : Gln 72
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human TNFSF18 consists of 361 amino acids and predicts a molecular mass of 40.9 kDa.
Protein length : Gln72-Ser199
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 [ Homo sapiens ]
Official Symbol : TNFSF18
Synonyms : TNFSF18; AITRL; hGITRL; TL6; AITR ligand; GITR ligand; GITRL; MGC138237;
Gene ID : 8995
mRNA Refseq : NM_005092
Protein Refseq : NP_005083
MIM : 603898
UniProt ID : Q9UNG2

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